Systemic markers of oxidative status and colorectal adenomatous polyps
نویسندگان
چکیده
منابع مشابه
Fasting Hyperglycemia and Insulin Resistance in Colorectal Adenomatous Polyps
OBJECTIVES: To investigate fasting glucose, glucose tolerance, insulin resistance and insulin–like growth factor 1 in patients with or without colorectal polyps. MATERIALS AND METHODS: In this cross-sectional study, we evaluated fasting glucose, insulin, insulin–like growth factor 1 (IGF-1), lipid profile and glucose tolerance test in 103 patients undergoing colonoscopy (52 normal and 53 wit...
متن کاملEpidemiology of colorectal adenomatous polyps.
Colorectal cancer is currently the second leading cause of cancer death in the United States (1); nearly 7% of Americans are expected to develop this disease within their lifetime (2). Efforts to identify causes and effective preventive measures for this disease have led to the hypothesis that adenomatous polyps (adenomas), benign tumors that arise in the large bowel, are precursor lesions for ...
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BACKGROUND Putrescine, spermidine, and spermine are the polyamines required for human cell growth. The inhibition of ornithine decarboxylase (ODC), which is the rate-limiting enzyme of polyamine biosynthesis, decreases tumor growth and the development of colorectal adenomas. A database was developed to estimate dietary polyamine exposure and relate exposure to health outcomes. OBJECTIVE We hy...
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Colorectal adenomas and possibly some hyperplastic polyps are precursors of colorectal cancer. Tobacco use is associated in epidemiologic studies with these polyps, although links between smoking and colorectal cancer are less consistent. To characterize the role of tobacco in early colorectal carcinogenesis, we compared tobacco use among 4,383 subjects with histologically verified benign (hype...
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Iron has been suggested to be a risk factor for colorectal neoplasia. Some individuals who are heterozygous for mutations in the hemochromatosis gene (HFE) have higher than average serologic measures of iron. We therefore investigated whether heterozygosity for HFE mutations was related to risk of advanced distal adenoma and whether the relationship was affected by dietary iron intake. In the P...
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ژورنال
عنوان ژورنال: Annals of Epidemiology
سال: 2012
ISSN: 1047-2797
DOI: 10.1016/j.annepidem.2012.05.001